DDGEL/DDCHIP: Web-Based Systems for Analysis of 2-D Gel Electrophoresis Images and DNA Macro/Micro Array Images
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چکیده
We have been developing a web-based software tool named DDGEL [3] for analysis of two-dimensional (2-D) gel electrophoresis image data obtained by the RLGS (Restriction Landmark Genomic Scanning) method. The RLGS method has been developed in order to detect and analyze the genetic alterations by observing the entire genomic DNA after separating DNA fragments in a single 2-D slab gel [2]. DDGEL has the following functions: (1) User identification/registration, (2) Spot detection, (3) Modification of spot data, (4) Database of reference gel image/spot data, (5) Addition and modification of comments on image/spot data, (6) Spot matching (under construction). Recently, we began to develop a web-based software tool for analyzing image data obtained from DNA macro arrays and/or DNA micro arrays. This tool is named DDCHIP. In this short article, we briefly report a recent improvement on DDGEL and an overview of DDCHIP.
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تاریخ انتشار 1999